What about CIS patients with high probability to develop MS? (Such as + CSF plus typical MS MRI, but not meeting 2010 McDonald criteria)? May they be enrolled?

What about CIS patients with high probability to develop MS? (Such as + CSF plus typical MS MRI, but not meeting 2010 McDonald criteria)? May they be enrolled?

Yes, CIS patients may be enrolled. However, RIS patients are excluded.

11/13/2015